ANSES warning on certain food supplements

ANSES, the National Food Safety Agency, published in its latest recommendation (1) a warning against the use of food supplements based on p-synphrine, a substance present in orange peel. bitter.

context

Many people who have overweight problems use dietary supplements. In the composition of some products, p-synphrine is present claiming a reduction in fat mass or a correction of body composition.

However, ANSES has received 40 reports of adverse effects (including 18 admissible) which could be linked to the consumption of food supplements using this famous ingredient. Reports which thus prompted ANSES to self-seize in the context of carrying out an expertise relating to these food supplements.

These cases include cardiovascular effects, liver damage, hyperphosphatemia and neurological damage.

Adverse effects are linked to excessive consumption of these products. ANSES recommends a dose of 20mg/d, which corresponds to a dose ingested by heavy consumers of citrus fruits. Indeed, 95% of people who consume citrus fruits in their daily diet reach a dose of p-synphrine not exceeding 20 mg/day. But like all substances that are concentrated in food supplements, the risk comes from the fact that one absorbs at once much more than any diet could provide.
In addition, she recommends not combining this substance with caffeine. Recommendations that are already found in other countries such as Germany. The Canadian government even recently banned this combination, the supplements were taken off the market. (source? I could not verify this statement about Germany and Canada)
On the other hand, for athletes who resort to this type of supplementation (supplementation?), they lose all the benefit of sport in particular (missing a word) its hypotensive effect whereas the cocktail has a hypertensive effect.
ANSES totally advises against the consumption of p-synephrine by populations at increased risk of adverse effects, such as people on special treatment for hypertension, heart disease or depression. Pregnant or breastfeeding women, children or adolescents are also affected by this warning.
This is not the first time that the dangerousness of food supplements has been pointed out. In January 2014, food supplements for muscle building and weight loss were the subject of a warning, accused of being the cause of acute hepatitis (hepatitis rather I suppose?).
Orange juice, squeezed oranges and marmalade can continue to be consumed (to be consumed rather than “to be consumed”, right?) without moderation.

Stephen
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Stephen Paul is the lead author and founder of My Health Sponsor. Holder of a diploma in health and well-being coaching with more than 200 articles in the field of health, he makes it a point of honor to offer advice based on reliable information, based on scientific research, and verified by health professionals.